The Calcium-Sensing Receptor (CaSR) is a crucial protein that helps regulate calcium levels in the body. It plays a significant role in various metabolic and endocrine disorders, influencing ...

CaSR is expressed almost ubiquitously. CaSR interacts with multiple heterotrimeric G protein subtypes thereby regulating highly divergent downstream signaling pathways, depending upon cellular context ...

Introduction Activating mutation of the calcium sensing receptor (CaSR), with gain in function in the renal tubule and the parathyroid gland, is associated with hypocalcaemia hypercalciuria.

Jonathan Javitch, MD, Ph.D., professor of experimental therapeutics in psychiatry and an expert on cell signaling, provided ...