A group of scientists in China has revealed a novel mechanism whereby a short form of IL-18, generated by caspase-3 cleavage ...

The authors postulated that dying cells in wounded tissues might signal to stem and progenitor ... and MEFs deficient in caspase 3 and caspase 7, which are essential apoptotic proteases, as ...

Apoptosis is dependent on caspase activation, whereas the caspase-independent necrotic signaling pathway remains ... in T cells requires FADD. Figure 3: RIP binds to Fas and signals necrotic ...