CRISPR-Cas9 is not the first method available to scientists for modifying DNA; it is by far, however, the easiest to use. With CRISPR-Cas9, the crRNA/tracrRNA sequence or an artificial guide RNA ...

Cas9 has several binding steps to help it home in on the right section of DNA when it’s assigned a gene to edit, but no system is perfect—the nuclease still occasionally binds to the wrong stretch of ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

Using SpCas9 variants, Cas9-NG, SpG and SpRY in Chinese cabbage and cabbage improved the editing capability of CRISPR/Cas9 technology and expanded the application of CRISPR/Cas9 technology in ...

The Charcot-Marie-Tooth Association (CMTA) has announced a $300,000 investment in a groundbreaking gene editing project aimed ...

This study shows that RNA decay rather than the presence of premature termination codons triggers a TA-like response.

Sahana is a science journalist and an intern at The Scientist, with a background in neuroscience and microbiology. She has previously written for Live Science, Massive Science, and eLife. View Full ...