“Given that there was little effect of MMP-13 abrogation on joint pathology other than cartilage erosion in this model, we plan to investigate whether there is any evidence of altered pain in ...

Connective tissues consist of ligaments, cartilage and tendons. A joint is held together by ligaments which give the joints their stability. Cartilage is found at the ends of bones and where ...

According to Stupp, testing in a sheep model was vital. Much like humans, sheep cartilage is stubborn and ... could be applied to joints during open-joint or arthroscopic surgeries.

Further, MOST includes MRI exams at multiple time points, providing sensitive measures of early joint structural change, including worsening cartilage damage.10 Using MOST data, our objectives were to ...

Connective tissues consist of ligaments, cartilage and tendons. A joint is held together by ligaments which give the joints their stability. Cartilage is found at the ends of bones and where ...

Protein disulfide isomerases (PDIs) are essential enzymes that facilitate the proper folding of proteins and maintain protein quality within the ...

But a study published yesterday (October 9) in Science Advances finds that we can generate new proteins in joint cartilage, and this ability is more pronounced in joints farther from the center of the ...

This important study focused on characterizing clonally derived MSC populations from the synovium of normal and osteoarthritis (OA) patients, demonstrating their potential to regenerate cartilage in ...