Unfortunately, the path towards disease-altering therapy in PD is ... coupled with previous research indicating that calcium signaling is involved in the selective degeneration of dopaminergic ...

These disruptions in calcium signaling affect rotavirus disease severity, providing new insights into how NSP4's function influences rotavirus virulence. The findings suggest that manipulating ...

New research by John Innes Centre has discovered a biological mechanism in plants could reduce the need for inorganic ...

Figuring out this process at the molecular level could increase understanding of how the brain works normally and in diseases where these processes go awry ... is having a huge effect on the way the ...

Further, the team found that the same molecular machinery controlling calcium release at muscle ... sites -- where calcium regulates neuronal signaling. Because of these clues, the researchers ...

These translational studies are aimed at developing new therapeutic targets for heart disease. Proper contraction and relaxation ... and their role in profibrotic signaling. New therapies in ...

Myeloid deficiency of the mitochondrial transacetylase tafazzin upregulates mtROS, disrupting UPR and calcium homeostasis, ...

Ossification of the posterior longitudinal ligament (OPLL) is a progressive spinal disease characterized by ectopic bone formation in the spine, leading to severe neurological symptoms due to spinal ...