研究结果显示,抗生素处理会削弱模拟禁食饮食的抗肿瘤效果。于是,研究人员分析了模拟禁食饮食对肠癌小鼠模型肠菌的影响。从分析结果来看,罗伊氏乳杆菌( Lactobacillus reuteri )和假长双歧杆菌( Bifidobacterium ...
一、研究背景 CD8 T 细胞在适应性免疫中对抗病原体起着关键作用,其具有多种功能表型,包括幼稚(na?ve)、记忆(memory)、效应记忆(effector memory)、效应(effector)和耗竭(exhausted)等,每种表型又包含多个亚表型。已有研究表明,特定抗原特异性的 T 细胞 ...
“身体是革命的本钱”,这句话到今天也不过时,对奇点糕这儿基本每天出镜的CD8 + T细胞更是特别正确,毕竟CD8 + T细胞经典的受抗原长期慢性刺激 ...
Although effector activity and memory formation in CD8 + T cells are known to depend on mTORC1-mediated metabolic regulation, the molecular mechanisms involved are lesser known. Here authors ...
In a new study published in Nature, led by scientists at the Allen Institute, La Jolla Institute for Immunology, and UC San Diego, researchers reveal how cells known as tissue-resident memory CD8 ...
The human immune system is like an army of specialized soldiers (immune cells) each with a unique role to play in fighting disease. In a new study published in Nature, led by scientists at the Allen ...
Image Credit: Shutterstock AI / Shutterstock.com A study published in Nature identifies a pathogenic subset of CD8+ memory T-cells that promote airway tissue inflammation and recurrent respiratory ...
Pathogen-fighting immune cells called tissue-resident memory CD8 T cells (TRM cells) go through a surprising transformation -- and relocation -- as they fight infections in the small intestine.
Developing effective treatments and understanding how the mechanism of the immune system have always been challenging for ...
A recent Cell Reports paper by the Oxenius group (IMB) demonstrates a function of targeted centrosome inheritance during CD8 + T cell division for the generation of memory precursor cells.
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