CD2, primarily present on T cells and NK cells, engages with CD58 (LFA-3) on antigen-presenting cells such as dendritic cells and macrophages. This CD2-CD58 interaction is crucial for immune cell ...

CD2 and LFA-1 expression also are up-regulated on memory T cells compared with naïve T cells. [18] Biologic agents have been developed to target a number of the identified ligands involved in the ...