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抗 CD19 外泌体递送系统:突破血脑屏障治疗中枢神经系统淋巴瘤的新 ...
此外,anti - CD19 - Exo - MTX 在体内主要在颅内区域有较强荧光信号,实现了靶向递送。 外泌体对 MTX 毒副作用的缓解作用:hAMSCs 来源的外泌体可部分逆转 MTX 诱导的神经毒性、肝损伤、肾损伤和骨髓抑制。蛋白质组学分析显示外泌体参与多种保护通路,实验也验证 ...
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