In a recent study, scientists have introduced an innovative imaging technique that provides an unparalleled view of the bone marrow’s intricate ...

Dr. Bo Shen, the lead author of the study, described the imaging technique as a significant advancement for bone marrow niche research. "This innovative approach allows us to visualize the ...

Bone marrow plays a crucial role in maintaining hematopoietic stem cells and bone homeostasis. However, research has been ...

Studies have also highlighted the presence of niche-specific regulatory T (Treg ... Various genetically modified mouse models were used to study bone marrow HSCs and their niches.

Lye highlights the importance of effectively integrating into the bone marrow niche, a specialized environment where stem cells are maintained and regulated for successful gene therapy.

In a recent study, scientists have introduced an innovative imaging technique that provides an unparalleled view of the bone marrow's intricate ...

Short-term co-culture setups might not capture the full extent of long-term interactions in the bone marrow niche. The study highlights how direct interaction with MSCs reprograms breast cancer ...

Myelodysplastic syndromes (MDS) are marked by ineffective hematopoiesis and dysplasia, which elevate the risk of progression to acute myeloid leukemia (AML). The inflammatory environment in MDS alters ...

They further found in 2023 that nerves promote bone marrow regeneration after irradiation or chemotherapy by activating signaling from β2 and β3 adrenergic receptors in the niche.