The potential must have both an attractive and a repulsive component if binding is to occur. The form of the potential energy as a function of lattice spacing (interatomic distance, r) in a solid is ...

We say that iron has a high binding energy per nucleon. Elements with lower and higher mass numbers per nucleon are less stable. The total mass of a nucleus is less than the total mass of the ...

Energy obtained from fusion and fission reactions is based on differences in the nuclear binding energy. The mass of the products of a fusion reaction is smaller than the mass of its reactants. The ...

Precise binding free energy calculations are crucial for efficient drug discovery. Traditional methods struggle with large chemical transformations, leading to errors and inefficiencies.

Precise calculations of binding free energy are pivotal in reducing the high costs and inefficiencies of drug discovery. A recent study presents PairMap, an innovative computational tool that ...

This scenario has led to the development of PairMap, a computational approach developed to address these challenges head-on. Relative binding free energy perturbation (RBFEP) calculations have ...