San Francisco 49ers star Christian McCaffrey left Sunday night’s 35-10 loss to the Buffalo Bills with a knee injury, but it appeared to be much worse than that. McCaffrey is believed to have ...

Fans tossed snowballs onto the field multiple times during the game, including once during a 49ers kick and another when Christian McCaffrey was leaving the field with a serious injury.

Christian McCaffrey's Season 'Potentially' Over After Knee Injury in 49ers' Loss to Bills ORCHARD PARK, N.Y. (AP) — San Francisco running back Christian McCaffrey suffered a knee injury that ...

San Francisco 49ers RB Christian McCaffrey powers through for a 19-yard run against the team's Week 13 matchup against the Buffalo Bills. Watch San Francisco 49ers tight end George Kittle's Week ...

49ers running back Christian McCaffrey suffered a PCL injury in Sunday’s 35-10 loss to the Buffalo Bills, coach Kyle Shanahan said, putting the San Francisco star’s season in question with ...

Christian McCaffrey followed a worrisome slide with a troubling exit to the locker room on a snowy night in Buffalo. McCaffrey slid down on a run without contact and was ruled out of the San ...

ORCHARD PARK, N.Y. -- San Francisco 49ers running back Christian McCaffrey suffered what is believed to be an injury to the posterior cruciate ligament in his right knee Sunday night, leaving the ...