BCR-ABL1 is an abnormal gene present in certain types of leukemia. Genetic testing for BCR-ABL1 helps doctors diagnose these cancers and assess their response to treatment. If you or someone you ...

为解决BCR::ABL1阳性白血病中CDK6高表达导致的代谢重编程及耐药问题，（第一作者工作单位）研究人员开展了一项关于CDK6在白血病细胞代谢调控中的作用机制研究。他们发现CDK6激酶活性对氧化磷酸化（OXPHOS）的调控至关重要，并揭示了其与NRF-1的竞争关系。

Enliven Therapeutics, Inc. (Enliven or the Company) (Nasdaq: ELVN), a clinical-stage biopharmaceutical company focused on the ...

We also report that the patient associated with the BCR-RET fusion protein didn’t ... Antibodies used recognized ABL1 (Merck-Calbiochem, Darmstadt, Germany, #OP20), AKT (Cell Signaling, Saint ...

MPNs are also grouped into two general categories based on whether they are associated with an abnormal gene called BCR-ABL1.

In The Lancet Hematology, Jorge E Cortes and colleagues1 report a phase 1/2 study on vodobatinib in patients with resistance ...

Hematopoietic and lymphocytic neoplasms (HLNs) are a diverse group of malignancies affecting blood and lymphatic systems, with outcomes varying from ...

(a) Peripheral blood smear in a patient with the chronic phase of chronic myeloid leukemia (CML) before treatment; (b) Detection of BCR::ABL1 fusion gene, p210 by RNA sequencing; (c) Peripheral ...

One-month qRT-PCR BCR::ABL1 transcript threshold to predict early recurrence in chronic phase CML patients attempting first treatment free remission.