BCR-ABL1 forms when two of your chromosomes accidentally swap DNA during cell division. When this occurs, the ABL1 gene on chromosome 9 fuses with the BCR gene on chromosome 22, creating a new ...

In the study, "Disease diagnostics using machine learning of B cell and T cell receptor sequences," published in Science, researchers analyzed BCR heavy chain and TCR beta chain sequences from 593 ...

BCR-ABL forms a dimer and/or tetramer through ... antibody (Calbiochem, San Diego, CA, USA). Cell line dependence on IL-3 and sensitivity to imatinib were tested independently in MTS-based ...

Genes that encode B cell receptors (BCRs ... of ‘fingerprint’ of current and prior exposures. Therefore, TCR and BCR sequencing could, in theory, inform disease diagnosis, but this is ...