点击蓝字关注我们【导读】通过B细胞和T细胞表达的免疫受体谱系，可以大致了解一个人的感染和疫苗接种史，以及其他与免疫相关的疾病。Zaslavsky等人开发了一个名为Mal-ID（免疫学诊断机器学习）的框架，用于解读人体血液样本中B和T细胞受体（BCR和 ...

肿瘤的研究一直是生命科学和基础医学领域中的热门话题，随着分子生物学和肿瘤生物学等学科的发展，人们逐渐明确了一系列与肿瘤发生和转移等密切关系的基因、蛋白，包括多种受体酪氨酸激酶（RTKs，如EGFR、ALK、c-Met、TRK、BCR-ABL等）和非R ...

BCR-ABL forms a dimer and/or tetramer through ... antibody (Calbiochem, San Diego, CA, USA). Cell line dependence on IL-3 and sensitivity to imatinib were tested independently in MTS-based ...

achieving up to 1.0 AUROC on independent BCR cohorts and 0.99 AUROC on TCR cohorts after threshold adjustments. Results showed that combined B and T cell analyses outperformed single-locus approaches.

In response to pathogens, vaccines, and other antigenic stimuli, BCR and TCR repertoires undergo changes through clonal expansion, somatic mutation, and selective reshaping of immune cell populations.

Parse’s latest innovations include the recent launch of their Evercode Penta kit, the largest ever single cell sequencing kit ...

Hematopoietic and lymphocytic neoplasms (HLNs) are a diverse group of malignancies affecting blood and lymphatic systems, with outcomes varying from ...

Scaling up single cell experiments—processing millions of ... Parse’s latest innovations also include Mouse BCR and Transgenic Mouse BCR, designed to support antibody discovery and immunology ...

Parse Biosciences, the leader in accessible and scalable single cell sequencing, today affirmed their plans to proceed with development and future ...