During the progression of atherosclerosis, development of plaques is initiated by the arterial accumulation and oxidation of low-density lipoproteins (LDLs). This initiates an inflammatory process ...
At the later stages of disease (whether atherosclerosis or obesity), macrophage death is generally assumed to have deleterious consequences, such as the rupture of vascular plaques and excess ...
An important mechanism responsible for the sudden and unpredictable onset of acute thrombosis is plaque rupture. [1] The risk of rupture depends more on the plaque's composition rather than its size.
Inflammation is known to present at all stages of atherosclerotic lesion/plaque development, which often progresses silently for decades, before the occurrence of acute clinical events.
Our opinion: At this point, we do not recommend changing exercise habits (including intensity) in asymptomatic athletes to reduce progression of coronary atherosclerosis, since current cross-sectional ...