The growing body of genetic and clinical data highlight the need to consider the role of structural components of the airway in the onset and propagation of asthma. In particular, the epithelium ...

46 Disruption of the airway epithelium could also impact on mucociliary clearance. In patients with asthma having EIB, an increase in the gene expression and release of the secreted or gel-forming ...

There is increasing evidence that suggests a major involvement of airway epithelial cells in the pathogenesis of both asthma and allergic rhinitis. Even in patients with rhinitis who do not have ...

[54] It is hypothesized that airway epithelial cells may act both as inflammatory initiators and as immunopathological feedback regulators between AR and asthma via the release of systemic ...

“We have seen that after the constriction caused by asthma, the airways become very small very quickly, which affects the ...

Mucus plugs are thick, sticky accumulations of mucus that can form in asthma patients resulting in the blockage of airways. The researchers identified a protein involved in the generation of ...