Limitations of the three putative mechanisms of amyloid fibril assembly for explaining Sup35 prion formation have led to the introduction of a fourth model — nucleated conformational conversion ...

Amyloid fibrils have been targeted in a variety of neurodegenerative diseases. The amyloid cascade hypothesis, on which many modern Alzheimer's treatments are based, presumes that these fibrils ...

Among these, several molecules, such as lysozyme, were shown to be involved in amyloid fibril formation. The findings were ...

A collaborative research group has uncovered a new mechanism in the growth of amyloid β (Aβ ... (HS-AFM), the team was able to observe Aβ fibril growth at the molecular level in real time.