The following is a summary of “Efficacy and safety of decitabine combined with arsenic trioxide in elderly high-risk ...

编辑推荐：针对55岁以上急性髓系白血病 (AML)患者预后差的难题，研究人员通过回顾性队列研究对比了半相合造血干细胞移植 (Haplo-HCT)与单纯化疗 (Chemo)的疗效。经倾向评分匹配后，Haplo组1年总生存率 (OS)达77.9% * ，显著高于化疗组的62.0%，且复发率降低至16.5%。该研究为老年AML患者提供了更优治疗选择。

The following represents disclosure information provided by authors of this manuscript. All relationships are considered compensated unless otherwise noted. Relationships are self-held unless noted. I ...

Avoidance of anthracyclines in the elderly is often desired, due to potential risk of anthracycline-related toxicities, such as congestive cardiac failure (CCF) and acute myeloid leukemia (AML).

By targeting AML this way, our approach has the potential to improve outcomes, particularly for elderly patients who have limited treatment options." ...

The trial indicated that 100% of AML patients treated with INB-100 post-hematopoietic stem cell transplantation (HSCT) remained in complete remission, with a median follow-up of 20.1 months ...