One thing does not change, though. The defending NFC champion 49ers are 5-6 and they need to get on a heater - which will be ...

The team is practicing in Santa Clara on Friday afternoon before flying to New York on Friday afternoon; the 49ers are ...

Heavy, lake-effect snow will fall on Buffalo this weekend as the 49ers arrive to face the Bills on Sunday night in the suburb ...

Matt Maiocco reveals which five 49ers players must step up in San Francisco's must-win Week 13 game against the Buffalo Bills ...

The San Francisco 49ers have released their final injury report ahead of their Week 13 bout with the Buffalo Bills.

The Chicago Bears announced Friday morning that they have fired head coach Matt Eberflus following the team's Thanksgiving ...

Eberflus was pressed on his job status following clock management issues in the Bears' loss to the Lions on Thanksgiving Day.

Eberflus lost his sixth game in a row and fell to 14-32 as he mismanaged the clock at the end of the Lions game Thursday.

The 49ers listed Brock Purdy as a limited participant while Nick Bosa and Trent Williams were among those not practicing ...

While the 49ers look like an easy opponent, San Francisco's health could be a major factor in the game, warns one NFL expert.

You can listen on SiriusXM satellite radio on channel 225 (Bills feed) and channel 226 (49ers feed), and on traditional radio ...

There is a High Risk of Weather Impact (ROWI) for the NFL's Sunday Night Football matchup between the San Francisco 49ers ...